(6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine

Base Information

• Chemical Name: (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine
• CAS No.: 645388-77-8
• Molecular Formula: C₁₇H₂₀BrNO₃
• Molecular Weight: 366.255
• Mol file: 645388-77-8.mol

Synonyms:(6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine

Chemical Property of (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine

There total 6 articles about (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-(4-methoxycyclohexa-1,4-dienyl)ethylamine (67175-79-5) + 6-bromo-3,4-methylenedioxybenzaldehyde (15930-53-7) → (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine (645388-77-8)

Guidance literature:

2-(4-methoxycyclohexa-1,4-dienyl)ethylamine; 6-bromo-3,4-methylenedioxybenzaldehyde; In methanol; for 2.5h; Inert atmosphere; Reflux;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ol3034093

Reference yield:

C17H18BrNO3 → (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine (645388-77-8)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1039/c4ob00126e

Reference yield:

[1-(6-Bromo-benzo[1,3]dioxol-5-yl)-meth-(Z)-ylidene]-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine → (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine (645388-77-8)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 0 ℃;

DOI:10.1055/s-2003-42053

upstream raw materials:

2-(4-methoxycyclohexa-1,4-dienyl)ethylamine

6-bromo-3,4-methylenedioxybenzaldehyde

Downstream raw materials:

4-{2-[(6-bromo-benzo[1,3]dioxol-5-ylmethyl)-amino]-ethyl}-cyclohex-2-enone

1,2,3,3a,4,5,12b,12c-octahydro-7H-1,3-benzodioxolo[5,6-c]pyrrolo[3,2,1-ij]quinoline

4-{2-[(6-bromo-benzo[1,3]dioxol-5-ylmethyl)-amino]-ethyl}-phenol

C₁₆H₂₀BrNO₃