Methyl 7-Methoxyindole-5-carboxylate

Base Information

Chemical Name:Methyl 7-Methoxyindole-5-carboxylate
CAS No.:180624-24-2
Molecular Formula:C₁₁H₁₁NO₃
Molecular Weight:205.213
Hs Code.:2933998090
European Community (EC) Number:814-224-9
Nikkaji Number:J767.736G

Synonyms:Methyl 7-Methoxyindole-5-carboxylate;180624-24-2;Methyl 7-methoxy-1H-indole-5-carboxylate;7-Methoxy-1H-indole-5-carboxylic acid methyl ester;MFCD03094980;SCHEMBL18031228;Methyl7-Methoxyindole-5-carboxylate;AC2461;AC-30058;CS-12200;SY039738;A925293

Suppliers and Price of Methyl 7-Methoxyindole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Methyl 7-methoxyindole-5-carboxylate
1 g
$ 1160.00

SynQuest Laboratories
Methyl 7-methoxyindole-5-carboxylate
250 mg
$ 464.00

Crysdot
Methyl7-methoxy-1H-indole-5-carboxylate 97%
1g
$ 612.00

AK Scientific
Methyl7-Methoxyindole-5-carboxylate
1g
$ 937.00

AccelPharmtech
7-methoxy-1H-Indole-5-carboxylicacidmethylester 97.00%
25G
$ 9110.00

AccelPharmtech
7-methoxy-1H-Indole-5-carboxylicacidmethylester 97.00%
5G
$ 4850.00

Total 3 raw suppliers

Chemical Property of Methyl 7-Methoxyindole-5-carboxylate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:244

Purity/Quality:

97% ^*data from raw suppliers

Methyl 7-methoxyindole-5-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C2C(=CC(=C1)C(=O)OC)C=CN2

Technology Process of Methyl 7-Methoxyindole-5-carboxylate

There total 4 articles about Methyl 7-Methoxyindole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 180624-21-9
methyl 4-amino-3-methoxy-5-[2-(trimethylsilyl)ethynyl]benzoate

: 180624-24-2
methyl 7-methoxy-1H-indole-5-carboxylate

Guidance literature:: With copper(l) iodide; In N,N-dimethyl-formamide; at 100 ℃; for 2.5h;
DOI:10.1021/jo952119+

Reference yield:

: 180624-10-6
4-amino-3-iodo-5-methoxybenzoic acid methyl ester

: 180624-24-2
methyl 7-methoxy-1H-indole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Et₃N / Pd(PPh₃)2Cl₂-CuI / 3 h / 0 - 20 °C

2: 69 percent / CuI / dimethylformamide / 2.5 h / 100 °C

With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In N,N-dimethyl-formamide; 1: cross-coupling / 2: Cyclization;
DOI:10.1021/jo952119+

Reference yield:

: 2486-69-3
3-methoxy-4-aminobenzoic acid

: 180624-24-2
methyl 7-methoxy-1H-indole-5-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / 2 h / 20 °C

2: 99 percent / bis(pyridine)iodonium(I) tetrafluoroborate; CF₃SO₃H / CH₂Cl₂ / 16 h / 20 °C

3: 90 percent / Et₃N / Pd(PPh₃)2Cl₂-CuI / 3 h / 0 - 20 °C

4: 69 percent / CuI / dimethylformamide / 2.5 h / 100 °C

With copper(l) iodide; thionyl chloride; trifluorormethanesulfonic acid; [bis(pyridine)iodine]⁺ tetrafluoroborate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In dichloromethane; N,N-dimethyl-formamide; 1: Esterification / 2: Iodination / 3: cross-coupling / 4: Cyclization;
DOI:10.1021/jo952119+