(4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene

Base Information

• Chemical Name: (4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene
• CAS No.: 418759-89-4
• Molecular Formula: C₂₄H₄₂O₅Si₂
• Molecular Weight: 466.765
• Mol file: 418759-89-4.mol

Synonyms:(4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene

Chemical Property of (4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene

There total 3 articles about (4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Deoxy-D-ribose (533-67-5) → (4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene (418759-89-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / dichlorodimethysilane / 25 °C

2: imidazole / pyridine

With 1H-imidazole; dimethylsilicon dichloride; In pyridine;

DOI:10.1021/ja012135q

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → (4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene (418759-89-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / dichlorodimethysilane / 25 °C

2: imidazole / pyridine

With 1H-imidazole; dimethylsilicon dichloride; In pyridine;

DOI:10.1021/ja012135q

Reference yield:

(3R,4S)-6-Benzyloxy-tetrahydro-pyran-3,4-diol (418760-06-2) + 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane (69304-37-6) → (4aS,9aR)-3-Benzyloxy-6,6,8,8-tetraisopropyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene (418759-89-4)

Guidance literature:

With 1H-imidazole; In pyridine;

DOI:10.1021/ja012135q

upstream raw materials:

(3R,4S)-6-Benzyloxy-tetrahydro-pyran-3,4-diol

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

2-Deoxy-D-ribose

benzyl alcohol