2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole

Base Information

Chemical Name:2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole
CAS No.:91944-43-3
Molecular Formula:C₂₇H₃₁N₃O₄S
Molecular Weight:493.627
Hs Code.:

Synonyms:2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole

Suppliers and Price of 2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of 2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole

There total 7 articles about 2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3-[3-(3,4-dimethoxyphenyl)-2-propylamino]-5-hydroxymethyl-2-phenyloxazolidine

: 584-08-7
potassium carbonate

: 98-59-9
p-toluenesulfonyl chloride

: 91944-43-3
2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole

Guidance literature:: In pyridine; water;

Reference yield:

: 3-[3-(3,4-dimethoxyphenyl)-2-propylamino]-5-hydroxymethyl-2-phenyloxazolidine

: 98-59-9
p-toluenesulfonyl chloride

: 91944-43-3
2-[p[[3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]-2-hydroxypropoxy]]-phenyl]-4-(2-thienyl)imidazole

Guidance literature:: In pyridine;

Reference yield:

: 91944-37-5
3-[4-(5-Thiophen-2-yl-1H-imidazol-2-yl)-phenoxy]-propane-1,2-diol

: 91944-43-3
1-[2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamino]-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)-phenoxy]-propan-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1: C₅H₅N*HCl, C₅H₅N / 1.5 h / Ambient temperature

2: NaOCH₃ / methanol; CH₂Cl₂ / 1.5 h / 0 - 4 °C

3: 30 h / 60 °C

With pyridine; sodium methylate; pyridine hydrochloride; In methanol; dichloromethane;
DOI:10.1021/jm00361a004