2-Guanidino-3-phenylpropanoic acid

Base Information

• Chemical Name: 2-Guanidino-3-phenylpropanoic acid
• CAS No.: 88728-27-2
• Molecular Formula: C10H13 N3 O2
• Molecular Weight: 207.232
• Hs Code.: 2925290090
• Mol file: 88728-27-2.mol

Synonyms:DL-Phenylalanine,N-(aminoiminomethyl)-

Chemical Property of 2-Guanidino-3-phenylpropanoic acid

Chemical Property:

• Vapor Pressure: 2.1E-07mmHg at 25°C
• Melting Point: 250 °C
• Refractive Index: 1.608
• Boiling Point: 408.4°C at 760 mmHg
• Flash Point: 200.8°C
• PSA: 99.20000
• Density: 1.31g/cm³
• LogP: 1.35630

Purity/Quality:

98%min ^*data from raw suppliers

2-Guanidino-3-phenylpropanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Guanidino-3-phenylpropanoic acid

There total 4 articles about 2-Guanidino-3-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.2%

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) + Aminoiminomethanesulfinic acid (1758-73-2) → α-guanidino-β-phenylpropionic acid (88728-27-2)

Guidance literature:

With sodium hydroxide; at 20 - 60 ℃;

DOI:10.1055/s-2000-8201

Reference yield:

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) + 2-methyl-isourea (2440-60-0) → α-guanidino-β-phenylpropionic acid (88728-27-2)

Guidance literature:

With methanol;

Reference yield:

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) + carbamimidothioic acid methyl ester (2986-19-8) → α-guanidino-β-phenylpropionic acid (88728-27-2)

Guidance literature:

With ammonium hydroxide;

upstream raw materials:

Phenylalanine

carbamimidothioic acid methyl ester

2-methyl-isourea

S-Methylisothiourea sulfate

Downstream raw materials:

2-amino-5-benzyl-1,5-dihydro-imidazol-4-one