rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

Base Information

Chemical Name:rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
CAS No.:138423-45-7
Molecular Formula:C₃₄H₃₇BrNO₇P
Molecular Weight:682.548
Hs Code.:

rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

Synonyms:rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

Suppliers and Price of rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

There total 1 articles about rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 138423-44-6
rac-<2R,3S(R)>-2-(3-bromo-2,2-dimethoxypropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)-1-azetidineacetic acid (2,2-dimethyl-1-oxopropyl)methyl ester

: 138423-45-7
rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

Guidance literature:: With hydrogen bromide; In acetone; at 0 ℃; for 0.333333h;
DOI:10.1021/jm00088a019

Reference yield: 63.0%

: 115699-47-3
6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid potassium salt

: 138423-45-7
rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

: 138444-28-7
rac-<2R,3S(R)>-6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid <<3-(1-hydroxyethyl)-1-<2-<(2,2-dimethyl-1-oxopropoxy)methoxy>-2-oxo-1-(triphenylphosphoranylidene)ethyl>-4-oxo-2-azetidinyl>acetyl>me.

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; for 17h; Ambient temperature;
DOI:10.1021/jm00088a019

Reference yield:

: 138423-45-7
rac-<2R,3S(R)>-2-(3-bromo-2-oxopropyl)-3-(1-hydroxyethyl)-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

: 140928-19-4
rac-<2R,3S(R)>-6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid <<3-<1-<(trimethylsilyl)oxy>ethyl>-1-<2-<(2,2-dimethyl-1-oxopropoxy)methoxy>-2-oxo-1-(triphenylphosphoranylidene)etyl>-4-oxo-2-azeti.>>

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / Et₃N / dimethylformamide / 17 h / Ambient temperature

2: pyridine / 22 h / Ambient temperature

With pyridine; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1021/jm00088a019