(+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride

Base Information

Chemical Name:(+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride
CAS No.:1355053-75-6
Molecular Formula:C₁₉H₂₀FNO₃*ClH
Molecular Weight:365.832
Hs Code.:

Synonyms:(+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride

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Chemical Property of (+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride

Chemical Property:

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Technology Process of (+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride

There total 1 articles about (+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1355053-75-6
(+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride

Guidance literature:

Reference yield:

: 1355053-75-6
(+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride

: 4865-84-3
2-(benzo[d]isoxazol-3-yl)acetic acid

: C₂₈H₂₅FN₂O₅

Guidance literature:: 2-(benzo[d]isoxazol-3-yl)acetic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

(+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield:

: 1355053-75-6
(+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride

: 581-96-4
2-naphthylacetic acid

: C₃₁H₂₈FNO₄

Guidance literature:: (+/-)-[4-fluoro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)phenoxy]acetic acid ethyl ester hydrochloride; In dichloromethane; at 20 ℃; for 1h;

2-naphthylacetic acid; With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In dichloromethane; at 20 ℃; for 1h;