Technology Process of C50H41BrO
There total 8 articles about C50H41BrO which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium phosphate; tetrakis(triphenylphosphine) palladium(0);
In
1,4-dioxane; water;
at 80 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/ol3017353
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: diethyl chlorophosphate; lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -78 - 20 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: iodine(I) bromide / dichloromethane / 2 h / -78 °C / Inert atmosphere
3.1: potassium phosphate; tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 3 h / 80 °C / Inert atmosphere
With
potassium phosphate; tetrakis(triphenylphosphine) palladium(0); iodine(I) bromide; diethyl chlorophosphate; lithium hexamethyldisilazane;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water;
3.1: Suzuki-Miyaura coupling;
DOI:10.1021/ol3017353
- Guidance literature:
-
Multi-step reaction with 2 steps
1: iodine(I) bromide / dichloromethane / 2 h / -78 °C / Inert atmosphere
2: potassium phosphate; tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 3 h / 80 °C / Inert atmosphere
With
potassium phosphate; tetrakis(triphenylphosphine) palladium(0); iodine(I) bromide;
In
1,4-dioxane; dichloromethane; water;
2: Suzuki-Miyaura coupling;
DOI:10.1021/ol3017353
