2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide

Base Information

• Chemical Name: 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide
• CAS No.: 1310569-12-0
• Molecular Formula: C₉H₅F₆NS
• Molecular Weight: 273.202
• Mol file: 1310569-12-0.mol

Synonyms:2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide

Chemical Property of 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide

There total 3 articles about 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1,1,1-Trichloro-2,2,2-trifluoroethane (354-58-5) + (E)-1-phenyl-N-(4-(trifluoromethyl)phenyl)methanimine (164362-55-4) → 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide (1310569-12-0)

Guidance literature:

With potassium phosphate; 1,10-Phenanthroline; silver fluoride; sulfur; copper(l) chloride; In 1,4-dioxane; water; at 120 ℃; for 4h;

Reference yield: 68.0%

1,1,1-Trichloro-2,2,2-trifluoroethane (354-58-5) + N-benzylidene-4-(trifluoromethyl)aniline (351-98-4) → 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide (1310569-12-0)

Guidance literature:

With sulfur; potassium phosphate; 1,10-Phenanthroline; water; magnesium sulfate; copper(l) chloride; In 1,4-dioxane; at 120 ℃; for 4h; Schlenk technique;

DOI:10.1016/j.jfluchem.2020.109640

Reference yield:

2,2,2-trifluoro-N-[4-(trifluoromethyl)phenyl]ethanimidoyl chloride (185315-30-4) → 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)ethanethioamide (1310569-12-0)

Guidance literature:

With sodium hydrosulfide monohydrate; In ethanol; at 20 ℃;

DOI:10.1016/j.jfluchem.2011.02.010

upstream raw materials:

2,2,2-trifluoro-N-[4-(trifluoromethyl)phenyl]ethanimidoyl chloride

1,1,1-Trichloro-2,2,2-trifluoroethane

(E)-1-phenyl-N-(4-(trifluoromethyl)phenyl)methanimine

N-benzylidene-4-(trifluoromethyl)aniline

Downstream raw materials:

C₁₈H₈F₁₂N₂S₂