2-bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

Base Information

• Chemical Name: 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
• CAS No.: 875781-45-6
• Molecular Formula: C13H9BrIN3O2S
• Molecular Weight: 478.108
• Hs Code.: 29339900
• Mol file: 875781-45-6.mol

Synonyms:2-Bromo-7-iodo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine;

Chemical Property of 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

Chemical Property:

• Vapor Pressure: 1.41E-12mmHg at 25°C
• Refractive Index: 1.777
• Boiling Point: 560.1 °C at 760 mmHg
• Flash Point: 292.6 °C
• PSA: 73.23000
• Density: 2.11 g/cm³
• LogP: 4.42460
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

2-Bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

There total 6 articles about 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-bromo-7-iodo-5H-pyrrolo[3,2-b]pyrazine (875781-44-5) + p-toluenesulfonyl chloride (98-59-9) → 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[3,2-b]pyrazine (875781-45-6)

Guidance literature:

2-bromo-7-iodo-5H-pyrrolo[3,2-b]pyrazine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h;

p-toluenesulfonyl chloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h;

Reference yield: 99.0%

2-bromo-5H-pyrrolo[2,3-b]pyrazine (875781-43-4) + p-toluenesulfonyl chloride (98-59-9) → 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[3,2-b]pyrazine (875781-45-6)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 3.33333h;

Reference yield: 67.69%

→ 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[3,2-b]pyrazine (875781-45-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

In N,N-dimethyl-formamide; at 0 ℃;

upstream raw materials:

2-bromo-5H-pyrrolo[2,3-b]pyrazine

p-toluenesulfonyl chloride

2-bromo-7-iodo-5H-pyrrolo[3,2-b]pyrazine

5-bromo-3-((trimethylsilyl)ethynyl)pyrazine-2-amine

Downstream raw materials:

2-bromo-7-(2-methoxy-phenyl)-5-(toluene-4-sulfonyl)-5h-pyrrolo[2,3-b]pyrazine

2-bromo-7-(1H-indol-5-yl)-5-tosyl-5H-pyrrolo[3,2-b]pyrazine

7-(1H-indol-5-yl)-2-(3,4,5-trimethoxyphenyl)-5H-pyrrolo[3,2-b]pyrazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 875781-45-6 2-bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

Send

Send

Metric Ton KG G Pound L ML

Send

Send