Technology Process of 5-(4-amino-2,6-dichloro-phenoxy)-3-methyl-1H-indole-2-carboxylic acid isopropylamide
There total 4 articles about 5-(4-amino-2,6-dichloro-phenoxy)-3-methyl-1H-indole-2-carboxylic acid isopropylamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
iron; acetic acid;
In
water;
at 20 ℃;
for 3h;
Acidic aqueous solution;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate / dimethyl sulfoxide / 17 h / 120 °C
2: iron; acetic acid / water / 3 h / 20 °C / Acidic aqueous solution
With
iron; potassium carbonate; acetic acid;
In
water; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: water / Alkaline aqueous solution
2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 18 h / 0 - 20 °C
3: boron dimethyl-trifluoro sulphide / 0 °C
4: potassium carbonate / dimethyl sulfoxide / 17 h / 120 °C
5: iron; acetic acid / water / 3 h / 20 °C / Acidic aqueous solution
With
boron dimethyl-trifluoro sulphide; water; iron; potassium carbonate; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
water; dimethyl sulfoxide; N,N-dimethyl-formamide;
