Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

Base Information

Chemical Name:Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine
CAS No.:117347-90-7
Molecular Formula:C₁₉H₁₉F₃N₄OS
Molecular Weight:408.447
Hs Code.:

Synonyms:Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

Suppliers and Price of Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

There total 6 articles about Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106771-59-9
2-(chloromethyl)-N,N-dimethylaniline

: 117296-80-7
1-[4-(2,2,2-Trifluoro-ethoxy)-pyridin-2-yl]-1,3-dihydro-imidazole-2-thione

: 117347-90-7
Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

Guidance literature:: With sodium hydroxide; In N,N-dimethyl-formamide; at 0 ℃; for 3h;
DOI:10.1021/jm950610n

Reference yield:

: 394-35-4
methyl 2-fluorobenzoate

: 117347-90-7
Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

Guidance literature:: Multi-step reaction with 4 steps

1: K₂CO₃ / dimethylformamide / Ambient temperature

2: LiAlH₄ / tetrahydrofuran

3: SOCl₂ / CHCl₃

4: NaOH / dimethylformamide / 3 h / 0 °C

With sodium hydroxide; lithium aluminium tetrahydride; thionyl chloride; potassium carbonate; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm950610n

Reference yield:

: 4707-56-6
(2-(dimethylamino)phenyl)methanol

: 117347-90-7
Dimethyl-(2-{1-[4-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl]-1H-imidazol-2-ylsulfanylmethyl}-phenyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / CHCl₃

2: NaOH / dimethylformamide / 3 h / 0 °C

With sodium hydroxide; thionyl chloride; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm950610n