3-BROMO-5-FLUORO-4-METHOXYANILINE

Base Information

• Chemical Name: 3-BROMO-5-FLUORO-4-METHOXYANILINE
• CAS No.: 875664-44-1
• Molecular Formula: C₇H₇BrFNO
• Molecular Weight: 220.041
• Hs Code.: 2922299090
• Mol file: 875664-44-1.mol

Synonyms:3-BROMO-5-FLUORO-4-METHOXYANILINE;4-AMINO-2-BROMO-6-FLUOROANISOLE;3-Bromo-5-fluoro-4-methoxyaniline 98%;3-Bromo-5-fluoro-4-methoxyaniline98%

Chemical Property of 3-BROMO-5-FLUORO-4-METHOXYANILINE

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• Melting Point: 70-73°C
• Refractive Index: 1.573
• Boiling Point: 290.56°C at 760 mmHg
• Flash Point: 129.527°C
• PSA: 35.25000
• Density: 1.617g/cm³
• LogP: 2.76020
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-Bromo-5-fluoro-4-methoxyaniline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BROMO-5-FLUORO-4-METHOXYANILINE

There total 3 articles about 3-BROMO-5-FLUORO-4-METHOXYANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C7H5BrFNO3 (875664-36-1) → C7H7BrFNO (875664-44-1)

Guidance literature:

With water; sodium hydroxide; at 40 ℃; for 4h; Temperature;

Reference yield:

3,4-difluoronitrobenzene (369-34-6) → C7H7BrFNO (875664-44-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid; N-Bromosuccinimide / 12 h / 20 °C

2: 2 h / 40 °C

3: sodium hydroxide; water / 4 h / 40 °C

With N-Bromosuccinimide; sulfuric acid; water; sodium hydroxide;

Reference yield:

1-bromo-2,3-difluoro-5-nitrobenzene (374633-24-6) → C7H7BrFNO (875664-44-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 2 h / 40 °C

2: sodium hydroxide; water / 4 h / 40 °C

With water; sodium hydroxide;

upstream raw materials:

3,4-difluoronitrobenzene

1-bromo-2,3-difluoro-5-nitrobenzene

C₇H₅BrFNO₃