Technology Process of 2-(-1-(3,4-dichlorophenyl)-1,2-dihydronaphthalen-3-yl)acetonitrile
There total 5 articles about 2-(-1-(3,4-dichlorophenyl)-1,2-dihydronaphthalen-3-yl)acetonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / tert-butyl methyl ether; toluene / 3 h / Reflux
2: sodium hydride / tetrahydrofuran; mineral oil / 2 h / 0 °C
With
sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; tert-butyl methyl ether; toluene; mineral oil;
DOI:10.1016/j.bmc.2010.10.034
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium tetrahydroborate / methanol / 3 h / 20 °C
2: / toluene / 100 °C
3: sodium hydrogen sulfate; osmium(VIII) oxide; water; 4-methylmorpholine N-oxide / acetone; toluene / 1.17 h / 20 °C
4: toluene-4-sulfonic acid / tert-butyl methyl ether; toluene / 3 h / Reflux
5: sodium hydride / tetrahydrofuran; mineral oil / 2 h / 0 °C
With
sodium tetrahydroborate; sodium hydrogen sulfate; osmium(VIII) oxide; water; sodium hydride; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; methanol; tert-butyl methyl ether; acetone; toluene; mineral oil;
DOI:10.1016/j.bmc.2010.10.034
