4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester

Base Information

• Chemical Name: 4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester
• CAS No.: 74670-98-7
• Molecular Formula: C₁₇H₂₃BrO₄S
• Molecular Weight: 403.337
• Mol file: 74670-98-7.mol

Synonyms:4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester

Chemical Property of 4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester

There total 3 articles about 4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

camphor (514-15-8,32989-00-7) → 4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester (74670-98-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 2.) HCl / 1.) THF, -78 deg C, 4 h, 2.) H₂O, room temperature

2: 1.5 g / LiAlH₄ / diethyl ether / Heating

3: pyridine

With hydrogenchloride; lithium aluminium tetrahydride; In pyridine; diethyl ether;

DOI:10.1021/ja00539a014

Reference yield:

ethyl endo-(7,7-dimethyl-2-hydroxynorbornan-2-yl)acetate (74670-96-5) → 4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester (74670-98-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.5 g / LiAlH₄ / diethyl ether / Heating

2: pyridine

With lithium aluminium tetrahydride; In pyridine; diethyl ether;

DOI:10.1021/ja00539a014

Reference yield:

endo-2-(2-hydroxyethyl)-7,7-dimethylnorbornan-2-ol (74670-97-6,103983-25-1) + 4-bromobenzenesulfonyl chloride (98-58-8) → 4-Bromo-benzenesulfonic acid 2-((1S,2R,4S)-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl)-ethyl ester (74670-98-7)

Guidance literature:

In pyridine;

DOI:10.1021/ja00539a014

upstream raw materials:

endo-2-(2-hydroxyethyl)-7,7-dimethylnorbornan-2-ol

4-bromobenzenesulfonyl chloride

camphor

ethyl endo-(7,7-dimethyl-2-hydroxynorbornan-2-yl)acetate