5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Base Information

Chemical Name:5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine
CAS No.:873792-87-1
Molecular Formula:C₆H₄BrClN₄
Molecular Weight:247.482
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00467634
Wikidata:Q82294673
Mol file:873792-87-1.mol

Synonyms:873792-87-1;5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine;5-Bromo-4-chloro-7H-pyrrolo[2,3-d] pyrimidin-2-amine;DTXSID00467634;MFCD12923105;AB10339;FT-0766898

Suppliers and Price of 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 95+%
1g
$ 651.00

Crysdot
5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 95+%
5g
$ 1956.00

Chemenu
5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 95%
5g
$ 1843.00

Chemenu
5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 95%
1g
$ 615.00

American Custom Chemicals Corporation
5-BROMO-4-CHLORO-1H-PYRROLO-[2,3-D]-PYRIMIDIN-2-AMINE 95.00%
5MG
$ 503.23

Total 4 raw suppliers

Chemical Property of 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.817
Boiling Point:519.449°C at 760 mmHg
Flash Point:267.953°C
PSA：67.59000
Density:2.084g/cm³
LogP:2.53720
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:245.93079
Heavy Atom Count:12
Complexity:181

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C2=C(N1)N=C(N=C2Cl)N)Br

Technology Process of 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine

There total 3 articles about 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-(5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2,2-trifluoro-acetamide

: 873792-87-1
2-amino-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 2h;
DOI:10.1021/jo0516640

Reference yield:

: 873792-85-9
N-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2,2-trifluoroacetamide

: 873792-87-1
2-amino-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: N-bromosuccinimide / CH₂Cl₂ / Heating

2: NH₃ / methanol / 2 h / 20 °C

With N-Bromosuccinimide; ammonia; In methanol; dichloromethane;
DOI:10.1021/jo0516640

Reference yield:

: 84955-31-7
4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine

: 873792-87-1
2-amino-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 3.58 h / 20 °C

2: N-bromosuccinimide / CH₂Cl₂ / Heating

3: NH₃ / methanol / 2 h / 20 °C

With pyridine; N-Bromosuccinimide; ammonia; In methanol; dichloromethane;
DOI:10.1021/jo0516640