Technology Process of benzyl 4-amino-3-({4-[bis(tert-butoxycarbonyl)amino]-2-methylbutan-2-yl}amino)benzoate
There total 5 articles about benzyl 4-amino-3-({4-[bis(tert-butoxycarbonyl)amino]-2-methylbutan-2-yl}amino)benzoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
acetic acid; zinc;
In
methanol;
for 0.333333h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: pyridine / dichloromethane / 16 h
2: potassium carbonate / acetonitrile / 16 h / 80 °C
3: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 16 h / 20 °C
4: zinc; acetic acid / methanol / 0.33 h
With
pyridine; di-isopropyl azodicarboxylate; potassium carbonate; acetic acid; triphenylphosphine; zinc;
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 2 h / 20 °C
2: pyridine / dichloromethane / 16 h
3: potassium carbonate / acetonitrile / 16 h / 80 °C
4: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 16 h / 20 °C
5: zinc; acetic acid / methanol / 0.33 h
With
pyridine; oxalyl dichloride; di-isopropyl azodicarboxylate; potassium carbonate; acetic acid; triphenylphosphine; zinc;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;