2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole

Base Information

• Chemical Name: 2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole
• CAS No.: 220666-57-9
• Molecular Formula: C₁₅H₁₉N₃O
• Molecular Weight: 257.335
• Mol file: 220666-57-9.mol

Synonyms:2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole

Chemical Property of 2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole

There total 3 articles about 2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2-acetyl-5-(N-benzyl-N'-methylamino)-1-methyl-4-nitropyrrole (220666-56-8) → 2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole (220666-57-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 24h; under 3102.89 Torr; Ambient temperature;

DOI:10.1002/jhet.5570350655

Reference yield:

benzyl-methyl-amine (103-67-3) → 2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole (220666-57-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / dimethylformamide / 3 h / Heating

2: 77 percent / H₂ / 10 percent Pd/C / ethanol / 24 h / 3102.89 Torr / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;

DOI:10.1002/jhet.5570350655

Reference yield:

2-acetyl-5-bromo-1-methyl-4-nitropyrrole (199684-03-2) → 2-acetyl-4-amino-5-(N-benzyl-N'-methylamino)-1-methylpyrrole (220666-57-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / dimethylformamide / 3 h / Heating

2: 77 percent / H₂ / 10 percent Pd/C / ethanol / 24 h / 3102.89 Torr / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;

DOI:10.1002/jhet.5570350655

upstream raw materials:

2-acetyl-5-(N-benzyl-N'-methylamino)-1-methyl-4-nitropyrrole

benzyl-methyl-amine

2-acetyl-5-bromo-1-methyl-4-nitropyrrole