Glycopyrrolate iodide

Base Information

• Chemical Name: Glycopyrrolate iodide
• CAS No.: 873295-32-0
• Molecular Formula: C₁₉H₂₈NO₃*I
• Molecular Weight: 445.341
• DSSTox Substance ID: DTXSID90469445
• Mol file: 873295-32-0.mol

Synonyms:873295-32-0;GLYCOPYRROLATE IODIDE;(1,1-dimethylpyrrolidin-1-ium-3-yl) 2-cyclopentyl-2-hydroxy-2-phenylacetate;iodide;Pyrrolidinium,3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethyl-, iodide (1:1);3-(2-Cyclopentyl-2-hydroxy-2-phenylacetoxy)-1,1-dimethylpyrrolidin-1-ium iodide;3-[(CYCLOPENTYLHYDROXYPHENYLACETYL)OXY]-1,1-DIMETHYL-PYRROLIDINIUM IODIDE;SCHEMBL135216;DTXSID90469445;AKOS030255251;FT-0669048;3-{[Cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidin-1-ium iodide

Chemical Property of Glycopyrrolate iodide

Chemical Property:

• PSA: 46.53000
• LogP: -0.58090
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 445.11139
• Heavy Atom Count: 24
• Complexity: 424

Purity/Quality:

98% ^*data from raw suppliers

Glycopyrrolate Iodide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+]1(CCC(C1)OC(=O)C(C2CCCC2)(C3=CC=CC=C3)O)C.[I-]
• Uses: As a novel pharmaceutical compound based on PDE IV inhibitors, Glycopyrrolate Iodide (Mixture of diastereomers) can be used in the treatment of respiratory complaints

Technology Process of Glycopyrrolate iodide

There total 3 articles about Glycopyrrolate iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glycopyrronium bromide (596-51-0,129784-12-9,201667-20-1,53808-86-9,58493-54-2) → 3-[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethylpyrrolidinium iodide (873295-32-0)

Guidance literature:

With sodium iodide; In dichloromethane; water; for 16h;

Reference yield:

→ 3-[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethylpyrrolidinium iodide (873295-32-0)

Guidance literature:

Reference yield:

→ (3R,2'R)-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidinium iodide (873295-32-0)

Guidance literature:

upstream raw materials:

glycopyrronium bromide