C₈H₁₁N*C₁₇H₂₄O₃

Base Information

• Chemical Name: C₈H₁₁N*C₁₇H₂₄O₃
• CAS No.: 1401298-95-0
• Molecular Formula: C₈H₁₁N*C₁₇H₂₄O₃
• Molecular Weight: 397.558
• Mol file: 1401298-95-0.mol

Synonyms:C₈H₁₁N*C₁₇H₂₄O₃

Chemical Property of C₈H₁₁N*C₁₇H₂₄O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₈H₁₁N*C₁₇H₂₄O₃

There total 4 articles about C₈H₁₁N*C₁₇H₂₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-phenyl-ethylamine (2627-86-3) + 4-(2-isobutyl-4-methylpentanoyl)benzoic acid (1401298-94-9) → C8H11N*C17H24O3 (1401298-95-0)

Guidance literature:

In diethyl ether;

DOI:10.1016/j.tet.2012.08.040

Reference yield:

2-isobutyl-4-methylpentanal (35155-65-8) → C8H11N*C17H24O3 (1401298-95-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / 1 h / -40 °C

1.2: 4 h / -40 °C

2.1: pyridinium chlorochromate / dichloromethane / 20 °C

3.1: lithium hydroxide / tetrahydrofuran; water / 4 h / 20 °C

4.1: diethyl ether

With isopropylmagnesium chloride; pyridinium chlorochromate; lithium hydroxide; In tetrahydrofuran; diethyl ether; dichloromethane; water;

DOI:10.1016/j.tet.2012.08.040

Reference yield:

2-isobutyl-4-methylpentanoic acid (5692-62-6) → C8H11N*C17H24O3 (1401298-95-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran

2.1: pyridinium chlorochromate / dichloromethane / 20 °C

3.1: isopropylmagnesium chloride / tetrahydrofuran / 1 h / -40 °C

3.2: 4 h / -40 °C

4.1: pyridinium chlorochromate / dichloromethane / 20 °C

5.1: lithium hydroxide / tetrahydrofuran; water / 4 h / 20 °C

6.1: diethyl ether

With lithium aluminium tetrahydride; isopropylmagnesium chloride; pyridinium chlorochromate; lithium hydroxide; In tetrahydrofuran; diethyl ether; dichloromethane; water;

DOI:10.1016/j.tet.2012.08.040

upstream raw materials:

2-isobutyl-4-methylpentanal

methyl 4-(1-hydroxy-2-isobutyl-4-methylpentyl)benzoate

(S)-1-phenyl-ethylamine

4-(2-isobutyl-4-methylpentanoyl)benzoic acid