(E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate

Base Information

Chemical Name:(E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate
CAS No.:1339193-32-6
Molecular Formula:C₁₅H₁₇NO₄S
Molecular Weight:307.37
Hs Code.:

Synonyms:(E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate

Suppliers and Price of (E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate

There total 2 articles about (E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1339193-17-7
(E)-benzyl 2-{(S)-3-[(1R)-1-(tert-butyldimethylsilanyloxy)ethyl]-1-(methylthio)-4-oxoazetidin-2-ylidene}acetate

: 1339193-32-6
(E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate

Guidance literature:: With boron trifluoride diethyl etherate; In acetonitrile; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/cmdc.201100282

Reference yield:

: 868082-97-7
[(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-(2E)-ylidene]-acetic acid benzyl ester

: 1339193-32-6
(E)-benzyl 2-((S)-3-((R)-1-hydroxyethyl)-1-(methylthio)-4-oxoazetidin-2-ylidene)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium diisopropyl amide / tetrahydrofuran / 4 h / -78 - 20 °C / Inert atmosphere

2: boron trifluoride diethyl etherate / acetonitrile / 0 - 20 °C / Inert atmosphere

With boron trifluoride diethyl etherate; lithium diisopropyl amide; In tetrahydrofuran; acetonitrile;
DOI:10.1002/cmdc.201100282