3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

Base Information

Chemical Name:3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline
CAS No.:207672-27-3
Molecular Formula:C₂₅H₂₄N₂O₂
Molecular Weight:384.478
Hs Code.:

Synonyms:3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

Suppliers and Price of 3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

There total 3 articles about 3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 564-94-3,18486-69-6
myrtenal

: 1-[2-(5-Benzyloxycarbonyl-pyridin-2-yl)-2-oxo-ethyl]-pyridinium; iodide

: 207672-27-3
3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

Guidance literature:: With ammonium acetate; formamide; at 75 ℃; for 6h;
DOI:10.1055/s-1998-2046

Reference yield:

: 94-44-0
benzyl nicotinate

: 207672-27-3
3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 39 percent / aq. H₂SO₄, FeSO₄, aq. t-BuOOH / 0.25 h / 5 - 10 °C

2: 98 percent / I₂ / 1.) reflux, 0.5 h, 2.) r.t., overnight

3: 70 percent / NH₄OAc, formamide / 6 h / 75 °C

With tert.-butylhydroperoxide; sulfuric acid; ammonium acetate; iodine; iron(II) sulfate; formamide;
DOI:10.1055/s-1998-2046

Reference yield:

: 207672-16-0
6-acetyl-nicotinic acid benzyl ester

: 207672-27-3
3-(5-Benzyloxycarbonyl-2-pyridyl)-7,7-dimethyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / I₂ / 1.) reflux, 0.5 h, 2.) r.t., overnight

2: 70 percent / NH₄OAc, formamide / 6 h / 75 °C

With ammonium acetate; iodine; formamide;
DOI:10.1055/s-1998-2046