16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Base Information

Chemical Name:16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide
CAS No.:867067-80-9
Molecular Formula:C₆₈H₉₃N₅O₈
Molecular Weight:1108.52
Hs Code.:

16-(3,5-di-<i>tert</i>-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2<i>H</i>-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Synonyms:16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Suppliers and Price of 16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

There total 10 articles about 16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 867067-79-6
16-(3,5-di-tert-butylphenoxy)hexadecanoic acid

: 2-amino-N-[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-acetamide; hydrochloride

: 867067-80-9
16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 10h;
DOI:10.1039/b506177f

Reference yield:

: 867067-72-9
3,5-bis(hydroxymethyl)aniline-tert-butyl carbamate

: 867067-80-9
16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Guidance literature:: Multi-step reaction with 6 steps

1: 65 percent / CBr₄; PPh₃ / tetrahydrofuran / 2 h / 20 °C

2: 69 percent / K₂CO₃ / dimethylformamide / 72 h / 85 °C

3: 100 percent / HCl / dioxane / 0 - 20 °C

4: 76 percent / DIEA; benzotriazole-1-yl-oxy-trispyrrolidinophosphonium*PF₆ / dimethylformamide / 10 h / 20 °C

5: 100 percent / HCl / dioxane / 0.5 h / 0 - 20 °C

6: 74 percent / benzotriazole-1-yl-oxy-trispyrrolidinophosphonium*PF₆; DIEA / dimethylformamide / 10 h / 20 °C

With hydrogenchloride; carbon tetrabromide; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1039/b506177f

Reference yield:

: 867067-73-0
(3,5-bis-bromomethyl-phenyl)-carbamic acid tert-butyl ester

: 867067-80-9
16-(3,5-di-tert-butyl-phenoxy)-hexadecanoic acid ({[(3,5-bis-{[(4,6-dimethyl-2-oxo-2H-chromen-7-yl)-ethyl-amino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-amide

Guidance literature:: Multi-step reaction with 5 steps

1: 69 percent / K₂CO₃ / dimethylformamide / 72 h / 85 °C

2: 100 percent / HCl / dioxane / 0 - 20 °C

3: 76 percent / DIEA; benzotriazole-1-yl-oxy-trispyrrolidinophosphonium*PF₆ / dimethylformamide / 10 h / 20 °C

4: 100 percent / HCl / dioxane / 0.5 h / 0 - 20 °C

5: 74 percent / benzotriazole-1-yl-oxy-trispyrrolidinophosphonium*PF₆; DIEA / dimethylformamide / 10 h / 20 °C

With hydrogenchloride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; potassium carbonate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1039/b506177f