2-(4-Methylphenoxy)propanohydrazide

Base Information

• Chemical Name: 2-(4-Methylphenoxy)propanohydrazide
• CAS No.: 83798-16-7
• Molecular Formula: C10H14 N2 O2
• Molecular Weight: 194.23
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID90390861
• Mol file: 83798-16-7.mol

Synonyms:2-(4-methylphenoxy)propanohydrazide;83798-16-7;2-(4-methylphenoxy)propanehydrazide;2-(p-Tolyloxy)propanehydrazide;Oprea1_016740;DTXSID90390861;BBL016776;MFCD02269956;STK434451;AKOS000305732;NCGC00324285-01;VS-05558;CS-0317131;AB01319670-02

Chemical Property of 2-(4-Methylphenoxy)propanohydrazide

Chemical Property:

• Vapor Pressure: 1.32E-06mmHg at 25°C
• Refractive Index: 1.539
• Boiling Point: 400°C at 760 mmHg
• Flash Point: 195.7°C
• PSA: 64.35000
• Density: 1.124g/cm³
• LogP: 1.84340
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 194.105527694
• Heavy Atom Count: 14
• Complexity: 189

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Methylphenoxy)propanohydrazide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)OC(C)C(=O)NN

Technology Process of 2-(4-Methylphenoxy)propanohydrazide

There total 1 articles about 2-(4-Methylphenoxy)propanohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(4-methylphenoxy)propanoate (70044-36-9) → 2-p-Tolyloxy-propionic acid hydrazide (83798-16-7)

Guidance literature:

With hydrazine hydrate;

DOI:10.1016/j.ejmech.2005.01.007

Reference yield: 80.0%

carbon disulfide (75-15-0,12122-00-8) + 2-p-Tolyloxy-propionic acid hydrazide (83798-16-7) → 5-(1-p-Tolyloxy-ethyl)-3H-[1,3,4]oxadiazole-2-thione (83797-83-5)

Guidance literature:

With potassium hydroxide; In methanol; for 6h; Heating;

Reference yield: 79.0%

3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carbonyl chloride (943982-60-3) + 2-p-Tolyloxy-propionic acid hydrazide (83798-16-7) → N'-(2-(4-methylphenoxy)propanoyl)-3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carbohydrazide

Guidance literature:

With potassium carbonate; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1002/jhet.3505

upstream raw materials:

ethyl 2-(4-methylphenoxy)propanoate

Downstream raw materials:

5-(1-p-Tolyloxy-ethyl)-3H-[1,3,4]oxadiazole-2-thione

C₁₇H₁₉N₃O₂S

C₁₇H₂₅N₃O₂S

4-phenyl-5-(1-p-tolyloxy-ethyl)-2,4-dihydro-[1,2,4]triazole-3-thione