{3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol

Base Information

• Chemical Name: {3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol
• CAS No.: 894094-41-8
• Molecular Formula: C₃₁H₃₂O₇
• Molecular Weight: 516.591
• Mol file: 894094-41-8.mol

Synonyms:{3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol

Chemical Property of {3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol

There total 8 articles about {3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C35H32O11 (1161867-70-4) → {3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol (894094-41-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; Reflux; Inert atmosphere;

Reference yield: 80.0%

C39H40O11 (894094-40-7) → {3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol (894094-41-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h;

DOI:10.1055/s-2006-926401

Reference yield:

diethyl 5-hydroxyisophthalate (39630-68-7) → {3-[3-benzyloxy-5-(3,5-bis-hydroxymethyl-phenoxymethyl)-benzyloxy]-5-hydroxymethyl-phenyl}-methanol (894094-41-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / K₂CO₃ / dimethylformamide / 60 h / 80 °C

2: 80 percent / LiAlH₄ / tetrahydrofuran / 6 h

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1055/s-2006-926401

upstream raw materials:

C₃₉H₄₀O₁₁

diethyl 5-hydroxyisophthalate

C₃₅H₃₂O₁₁

benzyl alcohol

Downstream raw materials:

C₆₃H₄₀F₂₄O₇

C₆₃H₅₆O₁₅

C₇₁H₆₄O₂₃

C₇₁H₆₄O₂₃