Ethyl (R)-(+)-4,5-epoxypentanoate

Base Information

• Chemical Name: Ethyl (R)-(+)-4,5-epoxypentanoate
• CAS No.: 136576-78-8
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.17

Synonyms:Ethyl (R)-(+)-4,5-epoxypentanoate

Chemical Property of Ethyl (R)-(+)-4,5-epoxypentanoate

Chemical Property:

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Technology Process of Ethyl (R)-(+)-4,5-epoxypentanoate

There total 1 articles about Ethyl (R)-(+)-4,5-epoxypentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

ethyl 3-(oxiran-2-yl)propanoate (73697-60-6) → (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran (32780-06-6) + Ethyl (R)-(+)-4,5-epoxypentanoate (136576-78-8)

Guidance literature:

With (R,R)-(salen)Co(OAc); In water; at 20 ℃; for 30h;

DOI:10.1039/b003793l

Reference yield: 87.0%

Ethyl (R)-(+)-4,5-epoxypentanoate (136576-78-8) → (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran (32780-06-6)

Guidance literature:

With trifluoroacetic acid; at -10 ℃; for 0.25h;

DOI:10.1039/b003793l

upstream raw materials:

ethyl 3-(oxiran-2-yl)propanoate

Downstream raw materials:

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran

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