3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril

Base Information

Chemical Name:3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril
CAS No.:135703-58-1
Molecular Formula:C₁₆H₁₁FN₄OS₂
Molecular Weight:358.42
Hs Code.:

Synonyms:3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril

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Chemical Property of 3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril

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Technology Process of 3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril

There total 3 articles about 3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 135703-48-9
6-amino-2-(4-fluor-phenacylthio)-4-methylthio-pyridin-3,5-dicarbonitril

: 135703-58-1
3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril

Guidance literature:: With triethylamine; In pyridine; for 1h; Heating;

Reference yield:

: 5147-80-8
[Bis(methylthio)methylene]malononitrile

: 135703-58-1
3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamin / dimethylformamide / 12 h / Ambient temperature

2: 83 percent / triethylamin / ethanol / 0.5 h / Ambient temperature

3: 78 percent / triethylamin / pyridine / 1 h / Heating

With triethylamine; In pyridine; ethanol; N,N-dimethyl-formamide;

Reference yield:

: 129048-41-5
6-amino-4-methylthio-2-thioxo-pyridin-3,5-dicarbonitril

: 135703-58-1
3,6-diamino-2-(4-fluor-benzoyl)-4-methylthio-thieno<2,3-b>pyridin-5-carbonitril

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / triethylamin / ethanol / 0.5 h / Ambient temperature

2: 78 percent / triethylamin / pyridine / 1 h / Heating

With triethylamine; In pyridine; ethanol;