2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid

Base Information

Chemical Name:2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid
CAS No.:1401792-14-0
Molecular Formula:C₁₆H₂₀N₄O₄
Molecular Weight:332.359
Hs Code.:

Synonyms:2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid

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Chemical Property of 2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid

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Technology Process of 2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid

There total 1 articles about 2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1225591-12-7
methyl (S)-2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)-propanoate

: 1401792-14-0
2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 100 ℃; for 0.166667h; Microwave irradiation;

Reference yield: 59.0%

: 1225591-16-1
1-(4-cyclohexylpiperidin-4-yl)butan-1-one

: 1401792-14-0
2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid

: 76-05-1
trifluoroacetic acid

: 1-[2-(4-butyryl-4-cyclohexylpiperidin-1-yl)-1-(4-methoxybenzyl)-2-oxoethyl]-3-[2-(1H-imidazol-4-yl)ethyl]urea trifluoroacetate

Guidance literature:: 1-(4-cyclohexylpiperidin-4-yl)butan-1-one; 2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

trifluoroacetic acid; In water; acetonitrile;

Reference yield: 48.0%

: 1401792-14-0
2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid

: 1225653-05-3
4-cyclohexyl-4-propionylpiperidine hydrochloride

: 76-05-1
trifluoroacetic acid

: (x)C₂HF₃O₂*C₃₀H₄₃N₅O₄

Guidance literature:: 2-{3-[2-(1H-imidazol-4-yl)ethyl]ureido}-3-(4-methoxyphenyl)propanoic acid; 4-cyclohexyl-4-propionylpiperidine hydrochloride; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

trifluoroacetic acid; In water; acetonitrile;