1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose

Base Information

• Chemical Name: 1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose
• CAS No.: 81076-81-5
• Molecular Formula: C₁₅H₁₈O₃
• Molecular Weight: 246.306
• Mol file: 81076-81-5.mol

Synonyms:1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose

Chemical Property of 1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose

There total 17 articles about 1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,6-anhydro-2-desoxy-2,4-di-C-methyl-3-O-benzyl-4-O-mesyl-β-D-galactopyranose (81076-80-4) → 1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose (81076-81-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In nitromethane; molecular sieves (4 Angstroem), nitromethane, reflux, 20 h;

DOI:10.1016/S0040-4039(01)82945-2

Reference yield: 84.0%

1,6-anhydro-2-desoxy-2-C-methyl-3-O-benzyl-β-D-xylohexapyranos-4-ylose (91510-66-6,97321-50-1) + Methylenetriphenylphosphorane (19493-09-5) → 1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose (81076-81-5)

Guidance literature:

In benzene; Heating;

DOI:10.1016/S0040-4039(01)90023-1

Reference yield: 59.0%

1,6-anhydro-2-desoxy-2,4-di-C-methyl-3-O-benzyl-4-O-mesyl-β-D-galactopyranose (81076-80-4) → 1,6-anhydro-3-O-benzyl-2,4-dideoxy-2-C-methyl-4-methylene-β-D-xylohexopyranose (81076-81-5) + 1,6-anhydro-2-desoxy-2,4-di-C-methyl-3-O-benzyl-4-O-mesyl-β-D-glucopyranose (81076-82-6)

Guidance literature:

With 4 A molecular sieve; In nitromethane; for 19h; Heating;

DOI:10.1007/BF00958405

upstream raw materials:

methyl triphenylphosphonium bromide

1,6-anhydro-2-desoxy-2-C-methyl-3-O-benzyl-β-D-xylohexapyranos-4-ylose

1,6-anhydro-2-desoxy-2,4-di-C-methyl-3-O-benzyl-4-O-mesyl-β-D-galactopyranose

Methylenetriphenylphosphorane

Downstream raw materials:

1,6-anhydro-2,4-didesoxy-2,4-di-C-methyl-3-O-benzyl-β-D-galactopyranose

1,6-anhydro-2,4-didesoxy-2,4-di-C-methyl-3-O-benzyl-β-D-glucopyranose

1,6-anhydro-2-desoxy-2,4-di-C-methyl-3-O-benzyl-β-D-galactopyranose

1,6-anhydro-3-O-benzyl-2-desoxy-2,4-di-C-methyl-β-D-glucopyranose