1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

Base Information

Chemical Name:1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one
CAS No.:1335201-21-2
Molecular Formula:C₂₄H₂₅BrO₃
Molecular Weight:441.365
Hs Code.:

Synonyms:1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

Suppliers and Price of 1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

There total 3 articles about 1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₄H₂₇BrO₃

: 1335201-21-2
1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

Guidance literature:: With Dess-Martin periodane; In dichloromethane; for 1.5h; Inert atmosphere;
DOI:10.1021/ol202178t

Reference yield:

: 22125-55-9
4,4'-(2,2-dibromocyclopropane-1,1-diyl)bis(methoxybenzene)

: 1335201-21-2
1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: Dess-Martin periodane / dichloromethane / 1.5 h / Inert atmosphere

With n-butyllithium; Dess-Martin periodane; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ol202178t

Reference yield:

: 23151-06-6
2,2-dimethyl-pent-4-ynal

: 1335201-21-2
1-(1-bromo-2,2-bis(4-methoxyphenyl)cyclopropyl)-2,2-dimethylpent-4-yn-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: Dess-Martin periodane / dichloromethane / 1.5 h / Inert atmosphere

With n-butyllithium; Dess-Martin periodane; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ol202178t