4-METHYL-D3-CATECHOL

Base Information

• Chemical Name: 4-METHYL-D3-CATECHOL
• CAS No.: 83719-41-9
• Molecular Formula: C₇H₈O₂
• Molecular Weight: 127.115
• Mol file: 83719-41-9.mol

Synonyms:4-METHYL-D3-CATECHOL;4-Methyl-D3-catechol (1,2-Dihydroxy-4-methylbenzene)

Chemical Property of 4-METHYL-D3-CATECHOL

Chemical Property:

• PSA: 40.46000
• LogP: 1.40620

Purity/Quality:

4-Methyl-d3-catechol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Methyl-d3-catechol (CAS# 83719-41-9) is a useful isotopically labeled research compound.

Technology Process of 4-METHYL-D3-CATECHOL

There total 3 articles about 4-METHYL-D3-CATECHOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C9H9(2)H3O2 → 4-methyl-d3-catechol (83719-41-9)

Guidance literature:

With hydrogen iodide; Heating;

DOI:10.1021/ja00389a075

Reference yield:

3,4-dimethoxybenzoic acid chloride (3535-37-3) → 4-methyl-d3-catechol (83719-41-9)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlD₄/AlCl₃

2: BBr₃

With aluminium trichloride; lithium aluminium deuteride; boron tribromide;

DOI:10.1021/ja00252a013

Reference yield:

3,4-dimethoxybenzoic acid chloride (3535-37-3) → 4-methyl-d3-catechol (83719-41-9)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlD₄, AlCl₃

2: HI / Heating

With aluminium trichloride; lithium aluminium deuteride; hydrogen iodide;

DOI:10.1021/ja00389a075

upstream raw materials:

3,4-dimethoxybenzoic acid chloride

Refernces

• 1、 Que, Lawrence,Lauffer, Randall B.,Lynch, John B.,Murch, Bruce P.,Pyrz, Joseph, W.. "Elucidation of the Coordination Chemistry of the Enzyme-Substrate Complex of Catechol 1,2-Dioxygenase by NMR Spectroscopy". . p. 5381 - 5385. Retrieved 2007/10/02.