Technology Process of 4-[2'-(naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-(2-o-tolyl-ethyl)-1H-[1,2,3]triazole
There total 3 articles about 4-[2'-(naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-(2-o-tolyl-ethyl)-1H-[1,2,3]triazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; cesium fluoride;
In
tetrahydrofuran;
at 120 ℃;
under 12929 Torr;
Inert atmosphere;
Microwave irradiation;
DOI:10.1021/jm101238d
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium azide; copper(II) sulfate / water; tert-butyl alcohol / 0.5 h / 120 °C / 12929 Torr / Microwave irradiation
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; cesium fluoride / tetrahydrofuran / 120 °C / 12929 Torr / Inert atmosphere; Microwave irradiation
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium azide; copper(II) sulfate; cesium fluoride;
In
tetrahydrofuran; water; tert-butyl alcohol;
2: Suzuki coupling;
DOI:10.1021/jm101238d
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium azide; copper(II) sulfate / water; tert-butyl alcohol / 0.5 h / 120 °C / 12929 Torr / Microwave irradiation
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; cesium fluoride / tetrahydrofuran / 120 °C / 12929 Torr / Inert atmosphere; Microwave irradiation
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium azide; copper(II) sulfate; cesium fluoride;
In
tetrahydrofuran; water; tert-butyl alcohol;
2: Suzuki coupling;
DOI:10.1021/jm101238d