ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Base Information

Chemical Name:ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside
CAS No.:257286-45-6
Molecular Formula:C₃₈H₅₅NO₁₂S
Molecular Weight:749.92
Hs Code.:

ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Synonyms:ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Suppliers and Price of ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

There total 8 articles about ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

: 257286-45-6
ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Guidance literature:: With hydrogenchloride; 3 A molecular sieve; sodium cyanoborohydride; In tetrahydrofuran; diethyl ether; for 0.5h;
DOI:10.1021/jo990979a

Reference yield:

: 206857-11-6
ethyl 3,4-O-isopropylidene-6-O-(1-methoxy-1-methylethyl)-1-thio-β-D-galactopyranoside

: 257286-45-6
ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: NaH / dimethylformamide / 4 h

2: HCl / H₂O; CH₂Cl₂

3: 91 percent / NaH / tetrahydrofuran / 3 h / 60 °C

4: 100 percent / TBAF / tetrahydrofuran / 1 h

5: 93 percent / Et₃N / CH₂Cl₂ / 2 h / 20 °C

6: 83 percent / NaH / tetrahydrofuran; dimethylsulfoxide / 4 h / 60 °C

7: 35 percent / NaCNBH₃; molecular sieves 3 Angstroem; HCl / tetrahydrofuran; diethyl ether / 0.5 h

With hydrogenchloride; 3 A molecular sieve; tetrabutyl ammonium fluoride; sodium hydride; sodium cyanoborohydride; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; 1: Alkylation / 2: Hydrolysis / 3: Substitution / 4: desilylation / 5: Substitution / 6: Substitution / 7: Reduction;
DOI:10.1021/jo990979a

Reference yield:

: 56245-60-4,686299-00-3
ethyl 1-thio-β-D-galactopyranoside

: 257286-45-6
ethyl 3,4-O-isopropylidene-2-O-p-methoxybenzyl-6-O-(3'-O-(methyl 2-acetamido-6-O-benzyl-2-deoxy-β-D-glucopyranos-3-oxy)propyl)-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1: TsOH

2: NaH / dimethylformamide / 4 h

3: HCl / H₂O; CH₂Cl₂

4: 91 percent / NaH / tetrahydrofuran / 3 h / 60 °C

5: 100 percent / TBAF / tetrahydrofuran / 1 h

6: 93 percent / Et₃N / CH₂Cl₂ / 2 h / 20 °C

7: 83 percent / NaH / tetrahydrofuran; dimethylsulfoxide / 4 h / 60 °C

8: 35 percent / NaCNBH₃; molecular sieves 3 Angstroem; HCl / tetrahydrofuran; diethyl ether / 0.5 h

With hydrogenchloride; 3 A molecular sieve; tetrabutyl ammonium fluoride; sodium hydride; sodium cyanoborohydride; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; 1: Substitution / 2: Alkylation / 3: Hydrolysis / 4: Substitution / 5: desilylation / 6: Substitution / 7: Substitution / 8: Reduction;
DOI:10.1021/jo990979a