2-(PROPYL-1,1-D2)PENTANOIC-3,3-D2 ACID

Base Information

Chemical Name:2-(PROPYL-1,1-D2)PENTANOIC-3,3-D2 ACID
CAS No.:87745-17-3
Molecular Formula:C₈H₁₆O₂
Molecular Weight:148.182
Hs Code.:
Mol file:87745-17-3.mol

Synonyms:3,3,3',3'-Tetradeuterovalproicacid

Suppliers and Price of 2-(PROPYL-1,1-D2)PENTANOIC-3,3-D2 ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ValproicAcid-d4
10mg
$ 1210.00

Medical Isotopes, Inc.
ValproicAcid-d4
1 mg
$ 290.00

American Custom Chemicals Corporation
2-(PROPYL-1,1-D2)PENTANOIC-3,3-D2 ACID 95.00%
5MG
$ 495.84

Total 11 raw suppliers

Chemical Property of 2-(PROPYL-1,1-D2)PENTANOIC-3,3-D2 ACID

Chemical Property:

PSA：37.30000
LogP:2.28740
Storage Temp.:Refrigerator
Solubility.:Aqueous Base (Slightly), Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

ValproicAcid-d4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Valproic Acid-d4 is the labeled analogue of Valproic Acid (V094750), an antiepileptic; Anticonvulsant that also acts as a mood stabilizer for those with bipolar disorder.

Technology Process of 2-(PROPYL-1,1-D2)PENTANOIC-3,3-D2 ACID

There total 4 articles about 2-(PROPYL-1,1-D2)PENTANOIC-3,3-D2 ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 99-66-1
valproic acid

: 345909-03-7,87745-17-3,87745-18-4
valproic acid

Guidance literature:: valproic acid; With d8-isopropanol; 10% Pt/activated carbon; water-d2; at 120 ℃; for 24h;

With water; sodium hydroxide; at 70 ℃; for 24h; Reagent/catalyst;
DOI:10.1002/adsc.201600363

Reference yield: 96.2%

: 2-(propyl-1,1-d2)-N-(quinolin-8-yl)pentanamide-3,3-d₂

: 87745-17-3
β-deuterovalproic acid

Guidance literature:: 2-(propyl-1,1-d2)-N-(quinolin-8-yl)pentanamide-3,3-d₂; With sodium hydroxide; In methanol; for 36h; Reflux;

With hydrogenchloride; In water; ethyl acetate; pH=2;

Reference yield:

: 2936-08-5
valproyl chloride

: 87745-17-3
β-deuterovalproic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; dmap / dichloromethane / 0 - 20 °C / Inert atmosphere

2.1: palladium diacetate; water-d2 / 48 h / 140 °C / Sealed tube

3.1: sodium hydroxide / methanol / 36 h / Reflux

3.2: pH 2

With dmap; water-d2; palladium diacetate; triethylamine; sodium hydroxide; In methanol; dichloromethane;