[2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide

Base Information

• Chemical Name: [2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide
• CAS No.: 1093167-59-9
• Molecular Formula: C₃₀H₃₁NO₂S₃
• Molecular Weight: 533.78
• Mol file: 1093167-59-9.mol

Synonyms:[2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide

Chemical Property of [2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of [2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide

There total 1 articles about [2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(S)-α-(methylsulfenyl)-2-(p-tolylsulfinyl)toluene (852332-84-4) + C15H15NOS (86783-44-0) → [2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide (1093167-59-9)

Guidance literature:

(S)-α-(methylsulfenyl)-2-(p-tolylsulfinyl)toluene; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.0833333h; Inert atmosphere;

C₁₅H₁₅NOS; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; hexane; at -78 ℃; optical yield given as %de;

DOI:10.1021/jo802200f

Reference yield: 90.0%

[2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide (1093167-59-9) → [2S,3S]-2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)-propan-2-amine (1093167-83-9)

Guidance literature:

[2S,3S,S(R)]-N-{2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)propyl}-p-toluenesulfinamide; With methanol; trifluoroacetic acid; at 0 ℃; for 3h; Inert atmosphere;

With ammonia; In methanol;

DOI:10.1021/jo802200f

upstream raw materials:

(S)-α-(methylsulfenyl)-2-(p-tolylsulfinyl)toluene

C₁₅H₁₅NOS

Downstream raw materials:

[2S,3S]-2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-3-(methylsulfenyl)-propan-2-amine