cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

Base Information

Chemical Name:cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine
CAS No.:291306-34-8
Molecular Formula:C₂₀H₂₁Cl₂NO₂S
Molecular Weight:410.364
Hs Code.:

Synonyms:cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

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Technology Process of cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

There total 1 articles about cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 291306-20-2
(1S-cis )-4-(3,4-dichlorophenyl)-7-iodo-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine

: 3680-02-2
methyl ethenyl sulphone

: 291306-34-8
cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

Guidance literature:: With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine; In acetonitrile; for 4h; Heating / reflux;

Reference yield:

: 291306-34-8
cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

: 291305-61-8
Cis-(1S)-N-methyl-7-(2-(methylsulphonyl)ethyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride

Guidance literature:: cis-(1S)-N-methyl-7-(2-(methylsulphonyl)vinyl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine; With toluene-4-sulfonic acid hydrazide; In toluene; for 7h; Heating / reflux;

With hydrogenchloride; In diethyl ether; dichloromethane;