5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

Base Information

Chemical Name:5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide
CAS No.:1620517-06-7
Molecular Formula:C₂₆H₃₁N₅O₃
Molecular Weight:461.564
Hs Code.:

Synonyms:5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

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Chemical Property of 5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

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Technology Process of 5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

There total 3 articles about 5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1620517-16-9
5-(piperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

: 108-24-7
acetic anhydride

: 1620517-06-7
5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.ejmech.2014.06.011

Reference yield:

: 1620517-34-1
C₂₀H₂₀IN₃O₂

: 1620517-06-7
5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 20 °C

2: triethylamine / dichloromethane / 0 - 20 °C

With triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.ejmech.2014.06.011

Reference yield:

: 1620517-06-7
5-(4-acetylpiperazin-1-yl)-N-(3-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)pentanamide

Guidance literature:: With 3-Methylpyridine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;