4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole

Base Information

• Chemical Name: 4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole
• CAS No.: 696662-91-6
• Molecular Formula: C₂₂H₂₄N₄O₃
• Molecular Weight: 392.458
• Mol file: 696662-91-6.mol

Synonyms:4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole

Chemical Property of 4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole

There total 1 articles about 4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(2S)-ethoxy-3-{4-[5-methyl-2-phenyl-oxazol-4-yl-methoxy]-phenyl}-propyl methanesulfonate → 4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole (696662-91-6)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 100 ℃; for 6h;

DOI:10.1691/ph.2008.8534

Reference yield: 72.0%

4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole (696662-91-6) → (2S)-ethoxy-3-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-phenyl]-propylamine

Guidance literature:

4-[4-(3-azido-2S-ethoxy-propyl)-phenoxymethyl]-5-methyl-2-phenyl-oxazole; With triphenylphosphine; In tetrahydrofuran; at 27 ℃; for 10h;

With water; In tetrahydrofuran; at 27 ℃; for 10h;

DOI:10.1691/ph.2008.8534