4-Chloro-2-(diphenylmethylene)-1(2H)-naphthalenone

Base Information

• Chemical Name: 4-Chloro-2-(diphenylmethylene)-1(2H)-naphthalenone
• CAS No.: 135241-11-1
• Molecular Formula: C₂₃H₁₅ClO
• Molecular Weight: 342.825
• DSSTox Substance ID: DTXSID301229410
• Mol file: 135241-11-1.mol

Synonyms:4-Chloro-2-(diphenylmethylene)-1(2H)-naphthalenone;DTXSID301229410;135241-11-1

Chemical Property of 4-Chloro-2-(diphenylmethylene)-1(2H)-naphthalenone

Chemical Property:

• XLogP3: 6.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 342.0811428
• Heavy Atom Count: 25
• Complexity: 541

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=C2C=C(C3=CC=CC=C3C2=O)Cl)C4=CC=CC=C4

Technology Process of 4-Chloro-2-(diphenylmethylene)-1(2H)-naphthalenone

There total 4 articles about 4-Chloro-2-(diphenylmethylene)-1(2H)-naphthalenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2,2-dimethyl-4,4-diphenyl-6-chloro-1,3-dioxa-1,2,3,4-tetrahydrophenanthrene (136197-42-7) → 4-chloro-2-(diphenylmethylene)-1(2H)-naphthalenone (135241-11-1)

Guidance literature:

With hydrogenchloride; In acetic acid; at 110 ℃; for 0.333333h;

Reference yield: 88.0%

2-(diphenylmethylene)-1(2H)-naphthalenone (51431-87-9) → 4-chloro-2-(diphenylmethylene)-1(2H)-naphthalenone (135241-11-1)

Guidance literature:

With sodium acetate; chlorine; acetic acid; for 0.5h;

Reference yield:

2-(diphenylmethylene)-1(2H)-naphthalenone (51431-87-9) → 4-chloro-2-(diphenylmethylene)-1(2H)-naphthalenone (135241-11-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / HCl / 0.33 h / 20 °C

2: 73 percent / sodium acetate, chlorine / acetic acid / 0.33 h

3: 88 percent / HCl / acetic acid / 0.33 h / 110 °C

With hydrogenchloride; sodium acetate; chlorine; In acetic acid;

upstream raw materials:

2-(diphenylmethylene)-1(2H)-naphthalenone

2,2-dimethyl-4,4-diphenyl-6-chloro-1,3-dioxa-1,2,3,4-tetrahydrophenanthrene

2,2-dimethyl-4,4-diphenyl-1,3-dioxa-1,2,3,4-tetrahydrophenanthrene

Downstream raw materials:

2--1,4-naphthoquinone

3,4,4-trichloro-2-(diphenylmethylene)-3,4-dihydro-1(2H)-naphthalenone

3,4-dichloro-2-(diphenylmethylene)-1(2H)-naphthalenone

(3,4-dichloro-1-hydroxy-2-naphthyl)diphenylmethanol