dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine

Base Information

• Chemical Name: dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine
• CAS No.: 101924-10-1
• Molecular Formula: C₂₄H₃₂N₆O₃
• Molecular Weight: 452.556
• Mol file: 101924-10-1.mol

Synonyms:dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine

Chemical Property of dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine

There total 8 articles about dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[(S)-1-[(1R,2R,3R)-3-(4-Dimethylamino-6-methyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxy-cyclopentylcarbamoyl]-2-(4-methoxy-phenyl)-ethyl]-carbamic acid benzyl ester (101924-09-8) → dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine (101924-10-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; for 1h;

Reference yield:

(2S)-2-[(benzyloxycarbonyl)amino]-3-(4-methoxyphenyl)propanoic acid (17554-34-6) → dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine (101924-10-1)

Guidance literature:

Multi-step reaction with 2 steps

1: N-hydroxysuccinimide, dicyclohexylcarbodiimide / dimethylformamide / 48 h / Ambient temperature

2: H₂ / Pd/C (10percent) / acetic acid / 1 h

With 1-hydroxy-pyrrolidine-2,5-dione; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In acetic acid; N,N-dimethyl-formamide;

Reference yield:

O-Methyltyrosine (6230-11-1) → dimethylamino-4--7 methyl-6-pyrrolo<2,3-d>pyrimidine (101924-10-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 91 percent

2: N-hydroxysuccinimide, dicyclohexylcarbodiimide / dimethylformamide / 48 h / Ambient temperature

3: H₂ / Pd/C (10percent) / acetic acid / 1 h

With 1-hydroxy-pyrrolidine-2,5-dione; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In acetic acid; N,N-dimethyl-formamide;

upstream raw materials:

[(S)-1-[(1R,2R,3R)-3-(4-Dimethylamino-6-methyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxy-cyclopentylcarbamoyl]-2-(4-methoxy-phenyl)-ethyl]-carbamic acid benzyl ester

O-Methyltyrosine

(2S)-2-[(benzyloxycarbonyl)amino]-3-(4-methoxyphenyl)propanoic acid

(+/-)acetamido-2α amino-5β cyclopentanol-1α