3,5-dimethylphenylamine hydrochloride

Base Information

• Chemical Name: 3,5-dimethylphenylamine hydrochloride
• CAS No.: 85518-76-9
• Molecular Formula: C₈H₁₂N*Cl
• Molecular Weight: 157.643
• Mol file: 85518-76-9.mol

Synonyms:3,5-dimethylphenylamine hydrochloride

Chemical Property of 3,5-dimethylphenylamine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-dimethylphenylamine hydrochloride

There total 3 articles about 3,5-dimethylphenylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C23H21NO3 → 1,3-diphenyl-propane-1,2,3-trione (643-75-4) + 3,5-dimethylphenylamine hydrochloride (85518-76-9)

Guidance literature:

With hydrogenchloride; In dichloromethane; water; at 20 ℃;

DOI:10.1016/j.tet.2016.03.093

Reference yield: 69.0%

N-acetyl-3,5-dimethylaniline (2050-45-5) + ethylmagnesium bromide (925-90-6) → 3,5-dimethylphenylamine hydrochloride (85518-76-9) + butanone (78-93-3)

Guidance literature:

N-acetyl-3,5-dimethylaniline; With 2-fluoropyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 ℃; for 0.5h;

ethylmagnesium bromide; With cerium(III) chloride; In tetrahydrofuran; dichloromethane; at -78 ℃; for 2h;

With hydrogenchloride; In ethyl acetate;

DOI:10.1016/j.cclet.2015.05.033

Reference yield:

3,5-dimethylaminoaniline (108-69-0) → 3,5-dimethylphenylamine hydrochloride (85518-76-9)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1039/c5cp02294k

upstream raw materials:

3,5-dimethylaminoaniline

N-acetyl-3,5-dimethylaniline

ethylmagnesium bromide

Downstream raw materials:

3,4,5-trimethylaniline

N⁶-(3,5-Dimethyl-phenyl)-9H-purine-2,6-diamine

(3,5-Dimethyl-phenyl)-(5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-4-yl)-amine

Hexamethylbenzene

Refernces

• 1、 Abdelhamid, Muhammad E.,Murdoch, Timothy,Greaves, Tamar L.,O'Mullane, Anthony P.,Snook, Graeme A.. "High-throughput approach for the identification of anilinium-based ionic liquids that are suitable for electropolymerisation". . p. 17967 - 17972. Retrieved 2015/07/07.