4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide

Base Information

• Chemical Name: 4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide
• CAS No.: 1401797-73-6
• Molecular Formula: C₂₁H₁₆ClNO₂S
• Molecular Weight: 381.883
• Mol file: 1401797-73-6.mol

Synonyms:4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide

Chemical Property of 4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide

Chemical Property:

Purity/Quality:

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• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide

There total 1 articles about 4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

4-Chlorobenzenesulfonamide (98-64-6) + 1,3-diphenyl-propen-3-one (614-47-1) → 4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide (1401797-73-6)

Guidance literature:

With titanium tetrachloride; triethylamine; In dichloromethane; at 0 ℃; for 18h; Reflux;

DOI:10.1002/ejoc.201701806

Reference yield: 67.0%

4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide (1401797-73-6) + methyl vinyl ketone (78-94-4,25038-87-3) → C25H22ClNO3S + C25H22ClNO3S

Guidance literature:

With triphenylphosphine; In dichloromethane; at 20 ℃; for 24h; optical yield given as %de;

DOI:10.1002/chem.201201318

Reference yield:

4-chloro-N-[(2E)-1,3-diphenylprop-2-en-1-ylidene]benzenesulfonamide (1401797-73-6) + N-aminophthalamide (1875-48-5) → 4-chloro-N-[[rel-(2R,3S)-1-(1,3-dioxoisoindol-2-yl)-3-phenylaziridin-2-yl](phenyl)methylene]benzenesulfonamide + 4-chloro-N-[[rel-(2R,3S)-1-(1,3-dioxoisoindol-2-yl)-3-phenylaziridin-2-yl](phenyl)methylene]benzenesulfonamide

Guidance literature:

With lead(IV) tetraacetate; potassium carbonate; In dichloromethane; at 0 ℃; for 0.75h; Overall yield = 78 %; Overall yield = 0.844 g;

DOI:10.1002/ejoc.201701806

upstream raw materials:

4-Chlorobenzenesulfonamide

1,3-diphenyl-propen-3-one