Technology Process of C25H22F3N5O2
There total 7 articles about C25H22F3N5O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
caesium carbonate;
tris-(dibenzylideneacetone)dipalladium(0); XPhos;
In
tert-butyl alcohol;
at 110 ℃;
for 20h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: caesium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane; water / 16 h / Reflux
2: hydrogen; thiophene / palladium 10% on activated carbon / methanol / 50 °C
3: caesium carbonate / tris-(dibenzylideneacetone)dipalladium(0); XPhos / tert-butyl alcohol / 20 h / 110 °C / Inert atmosphere
With
thiophene; hydrogen; caesium carbonate;
tris-(dibenzylideneacetone)dipalladium(0); tetrakis(triphenylphosphine) palladium(0); palladium 10% on activated carbon; XPhos;
In
methanol; 1,2-dimethoxyethane; water; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: caesium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane; water / 16 h / Reflux
2: hydrogen; thiophene / palladium 10% on activated carbon / methanol / 50 °C
3: caesium carbonate / tris-(dibenzylideneacetone)dipalladium(0); XPhos / tert-butyl alcohol / 20 h / 110 °C / Inert atmosphere
With
thiophene; hydrogen; caesium carbonate;
tris-(dibenzylideneacetone)dipalladium(0); tetrakis(triphenylphosphine) palladium(0); palladium 10% on activated carbon; XPhos;
In
methanol; 1,2-dimethoxyethane; water; tert-butyl alcohol;