C₄₁H₅₁NO₄Si

Base Information

• Chemical Name: C₄₁H₅₁NO₄Si
• CAS No.: 1428428-09-4
• Molecular Formula: C₄₁H₅₁NO₄Si
• Molecular Weight: 649.946
• Mol file: 1428428-09-4.mol

Synonyms:C₄₁H₅₁NO₄Si

Chemical Property of C₄₁H₅₁NO₄Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₄₁H₅₁NO₄Si

There total 11 articles about C₄₁H₅₁NO₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

C38H47NO4Si (1428428-08-3) + allyl bromide (106-95-6) → C41H51NO4Si (1428428-09-4)

Guidance literature:

With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil; at 0 - 60 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol400469w

Reference yield:

C34H37NO3Si → C41H51NO4Si (1428428-09-4)

Guidance literature:

Multi-step reaction with 5 steps

1: tetrahydrofuran / 12 h / Inert atmosphere; Reflux

2: lithium borohydride / ethanol / 4 h / Inert atmosphere

3: palladium 10% on activated carbon; ammonium formate / methanol / 12.5 h / Inert atmosphere

4: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / Inert atmosphere

5: sodium hydride / N,N-dimethyl-formamide; tetrahydrofuran; mineral oil / 2 h / 0 - 60 °C / Inert atmosphere

With lithium borohydride; palladium 10% on activated carbon; ammonium formate; sodium hydride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;

DOI:10.1021/ol400469w

Reference yield:

C34H39NO3Si → C41H51NO4Si (1428428-09-4)

Guidance literature:

Multi-step reaction with 6 steps

1: Dess-Martin periodane / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

2: tetrahydrofuran / 12 h / Inert atmosphere; Reflux

3: lithium borohydride / ethanol / 4 h / Inert atmosphere

4: palladium 10% on activated carbon; ammonium formate / methanol / 12.5 h / Inert atmosphere

5: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / Inert atmosphere

6: sodium hydride / N,N-dimethyl-formamide; tetrahydrofuran; mineral oil / 2 h / 0 - 60 °C / Inert atmosphere

With lithium borohydride; palladium 10% on activated carbon; ammonium formate; sodium hydride; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;

DOI:10.1021/ol400469w

upstream raw materials:

C₃₈H₄₇NO₄Si

allyl bromide

ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate

C₃₆H₄₁NO₄Si

Downstream raw materials:

C₃₇H₅₀N₂O₄S

C₅₈H₆₀N₄O₄

C₆₄H₇₃N₇O₆

C₃₇H₅₀N₂O₄S