C₂₃H₂₅F₂N₃O

Base Information

Chemical Name:C₂₃H₂₅F₂N₃O
CAS No.:1373945-70-0
Molecular Formula:C₂₃H₂₅F₂N₃O
Molecular Weight:397.468
Hs Code.:

C<sub>23</sub>H<sub>25</sub>F<sub>2</sub>N<sub>3</sub>O

Synonyms:C₂₃H₂₅F₂N₃O

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Chemical Property of C₂₃H₂₅F₂N₃O

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Technology Process of C₂₃H₂₅F₂N₃O

There total 3 articles about C₂₃H₂₅F₂N₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1373946-77-0
C₁₄H₁₇F₂NO₂

: 3468-18-6
1H-indole-4-methanamine

: 1373945-70-0
C₂₃H₂₅F₂N₃O

Guidance literature:: C₁₄H₁₇F₂NO₂; 1H-indole-4-methanamine; In benzene; for 16h; Reflux; Inert atmosphere;

With (4S,5S)-2-Chloro-3,4-dimethyl-2,5-diphenyl-[1,3,2]oxazasilolidine; In benzene; for 10h; optical yield given as %ee; enantioselective reaction; Reflux; Inert atmosphere;
DOI:10.1021/ol300922b

Reference yield:

: 328-51-8
2-oxooctanoic acid

: 1373945-70-0
C₂₃H₂₅F₂N₃O

Guidance literature:: Multi-step reaction with 3 steps

1.1: Dichloromethyl methyl ether / dichloromethane / 0.83 h / 50 °C / Inert atmosphere

2.1: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

3.1: benzene / 16 h / Reflux; Inert atmosphere

3.2: 10 h / Reflux; Inert atmosphere

With pyridine; Dichloromethyl methyl ether; In dichloromethane; benzene; 3.1: iso-Pictet-Spengler reaction / 3.2: iso-Pictet-Spengler reaction;
DOI:10.1021/ol300922b

Reference yield:

: 5509-65-9
2,6-difluoroaniline

: α-oxo-octanoyl chloride

: 1373945-70-0
C₂₃H₂₅F₂N₃O

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

2.1: benzene / 16 h / Reflux; Inert atmosphere

2.2: 10 h / Reflux; Inert atmosphere

With pyridine; In dichloromethane; benzene; 2.1: iso-Pictet-Spengler reaction / 2.2: iso-Pictet-Spengler reaction;
DOI:10.1021/ol300922b