2-(2-Pyridin-3-ylpiperidin-1-yl)ethanol

Base Information

• Chemical Name: 2-(2-Pyridin-3-ylpiperidin-1-yl)ethanol
• CAS No.: 86789-63-1
• Molecular Formula: C₁₂H₁₈N₂O
• Molecular Weight: 206.288
• DSSTox Substance ID: DTXSID70395697
• Mol file: 86789-63-1.mol

Synonyms:86789-63-1;2-(3,4,5,6-Tetrahydro-2H-[2,3']bipyridinyl-1-yl)-ethanol;2-(2-pyridin-3-ylpiperidin-1-yl)ethanol;Oprea1_737690;DTXSID70395697;AKOS030489818;FT-0764393;2-[2-(Pyridin-3-yl)piperidin-1-yl]ethan-1-ol

Chemical Property of 2-(2-Pyridin-3-ylpiperidin-1-yl)ethanol

Chemical Property:

• PSA: 36.36000
• LogP: 1.53880
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 206.141913202
• Heavy Atom Count: 15
• Complexity: 187

Purity/Quality:

97% ^*data from raw suppliers

2-(3,4,5,6-TETRAHYDRO-2H-[2,3']BIPYRIDINYL-1-YL)-ETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C(C1)C2=CN=CC=C2)CCO

Technology Process of 2-(2-Pyridin-3-ylpiperidin-1-yl)ethanol

There total 1 articles about 2-(2-Pyridin-3-ylpiperidin-1-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-(β-hydroxyethyl)anabasine (86789-63-1)

Guidance literature:

Anabasin, /BRN= 102378/;

DOI:10.1007/BF00565301

Reference yield: 90.0%

N-(β-hydroxyethyl)anabasine (86789-63-1) + phenyl isocyanate (103-71-9) → Phenyl-carbamic acid 2-(3,4,5,6-tetrahydro-2H-[2,3']bipyridinyl-1-yl)-ethyl ester (123556-20-7)

Guidance literature:

In toluene; for 7h; Heating;

DOI:10.1007/BF00598188

Downstream raw materials:

Phenyl-carbamic acid 2-(3,4,5,6-tetrahydro-2H-[2,3']bipyridinyl-1-yl)-ethyl ester