methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate

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Chemical Name:methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate
CAS No.:521985-08-0
Molecular Formula:C₂₄H₂₃N₇O₃
Molecular Weight:457.492
Hs Code.:

Synonyms:methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate

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Chemical Property of methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate

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Technology Process of methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate

There total 1 articles about methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid

: 521985-03-5
3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5'-carboxylic acid methyl ester

: 521985-08-0
methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate

Guidance literature:: 5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid; 3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5'-carboxylic acid methyl ester; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In DMF (N,N-dimethyl-formamide); at 50 ℃; for 24h;

In acetic acid; at 120 ℃; for 2h;

Reference yield:

: 521985-08-0
methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate

: 521985-07-9
5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylic acid

Guidance literature:: methyl 5-{4-[(5-methyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)carbonyl]piperazin-1-yl}pyrazine-2-carboxylate; With sodium hydroxide; In methanol; water; at 80 ℃; for 5h;

With hydrogenchloride; water; In methanol; at 0 ℃;

In acetic acid; at 120 ℃; for 2h;