1,2,4-Oxadiazol-5(4H)-one, 4-(3-bromo-4-fluorophenyl)-3-[4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl]-

Base Information

Chemical Name:1,2,4-Oxadiazol-5(4H)-one, 4-(3-bromo-4-fluorophenyl)-3-[4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl]-
CAS No.:1204669-63-5
Molecular Formula:C₁₃H₁₁BrFN₅O₄
Molecular Weight:400.164
Hs Code.:
Mol file:1204669-63-5.mol

Synonyms:4-(3-bromo-4-fluorophenyl)-3-{4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl}-1,2,4-oxadiazol-5(4H)-one

Suppliers and Price of 1,2,4-Oxadiazol-5(4H)-one, 4-(3-bromo-4-fluorophenyl)-3-[4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 6 raw suppliers

Chemical Property of 1,2,4-Oxadiazol-5(4H)-one, 4-(3-bromo-4-fluorophenyl)-3-[4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl]-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 1,2,4-Oxadiazol-5(4H)-one, 4-(3-bromo-4-fluorophenyl)-3-[4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl]-

There total 5 articles about 1,2,4-Oxadiazol-5(4H)-one, 4-(3-bromo-4-fluorophenyl)-3-[4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1204669-62-4
N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-[(2-methoxyethyl)amino]-1,2,5-oxadiazole-3-carboximidamide

: 530-62-1
1,1'-carbonyldiimidazole

: 1204669-63-5
4-(3-bromo-4-fluorophenyl)-3-{4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl}-1,2,4-oxadiazol-5(4H)-one

Guidance literature:: In ethyl acetate;

Reference yield: 96.0%

: 1204669-62-4
N-(3-bromo-4-fluorophenyl)-N‘-hydroxy-4-((2-methoxyethyl)amino)-1,2,5-oxadiazole-3-carboximidamide

: 530-62-1
1,1'-carbonyldiimidazole

: 1204669-63-5
4-(3-bromo-4-fluorophenyl)-3-{4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl}-1,2,4-oxadiazol-5(4H)-one

Guidance literature:: In ethyl acetate; at 60 ℃; for 0.5h; Inert atmosphere;

Reference yield:

: 1204669-60-2
N¹-hydroxy-4-((2-methoxyethyl)amino)-1,2,5-oxadiazole-3-carboximidamide

: 1204669-63-5
4-(3-bromo-4-fluorophenyl)-3-{4-[(2-methoxyethyl)amino]-1,2,5-oxadiazol-3-yl}-1,2,4-oxadiazol-5(4H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium chloride; sodium nitrite; hydrogenchloride / water; ethyl acetate / 3 - 20 °C

2: sodium hydrogencarbonate / water / 0.58 h / 60 °C

3: ethyl acetate / 0.33 h / 60 °C

With hydrogenchloride; sodium hydrogencarbonate; sodium chloride; sodium nitrite; In water; ethyl acetate;