2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide

Base Information

• Chemical Name: 2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide
• CAS No.: 201279-32-5
• Molecular Formula: C₁₆H₁₁ClN₂OS
• Molecular Weight: 314.795
• Mol file: 201279-32-5.mol

Synonyms:2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide

Chemical Property of 2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide

There total 1 articles about 2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-Chloro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide → 2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide (201279-32-5)

Guidance literature:

With sodium sulfide; In N,N-dimethyl-formamide; at 150 ℃; for 2h;

DOI:10.1007/BF02291947

Reference yield: 63.0%

2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide (201279-32-5) → 2-Hydrazino-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide

Guidance literature:

With hydrazine hydrate; In 1,4-dioxane; for 1h; Heating;

DOI:10.1007/BF02291947

Reference yield: 58.0%

ethyl 2-cyanoacetate (105-56-6) + 2-Thioxo-1,2-dihydro-quinoline-4-carboxylic acid (2-chloro-phenyl)-amide (201279-32-5) → [4-(2-Chloro-phenylcarbamoyl)-1H-quinolin-(2Z)-ylidene]-cyano-acetic acid ethyl ester

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 2h;

DOI:10.1007/BF02291947