1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)-1-cyclopropanamine

Base Information

Chemical Name:1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)-1-cyclopropanamine
CAS No.:308266-11-7
Molecular Formula:C₂₅H₂₇NO
Molecular Weight:357.495
Hs Code.:
DSSTox Substance ID:DTXSID80443890
Nikkaji Number:J1.413.011J
Wikidata:Q82261871

Synonyms:308266-11-7;1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)-1-cyclopropanamine;DTXSID80443890;1-(Dibenzylamino)-1-(benzyloxymethyl)cyclopropane;A820638;N,N-Dibenzyl-1-[(benzyloxy)methyl]cyclopropan-1-amine;1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)cyclopropan-1-amine

Suppliers and Price of 1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)-1-cyclopropanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)-1-cyclopropanamine

Chemical Property:

Boiling Point:466.8±25.0 °C(Predicted)
Density:1.12±0.1 g/cm3(Predicted)
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:9
Exact Mass:357.209264485
Heavy Atom Count:27
Complexity:394

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC1(COCC2=CC=CC=C2)N(CC3=CC=CC=C3)CC4=CC=CC=C4

Technology Process of 1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)-1-cyclopropanamine

There total 1 articles about 1-(phenylmethoxymethyl)-N,N-bis(phenylmethyl)-1-cyclopropanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 925-90-6
ethylmagnesium bromide

: N,N-dibenzyl-2-benzyloxyacetamide

: 308266-11-7
1-(benzyloxymethyl)-1-(dibenzylamino)cyclopropane

Guidance literature:: With methyltriisopropoxytitanium(IV); In tetrahydrofuran; diethyl ether; at 20 ℃;
DOI:10.1002/1099-0690(200009)2000:18<3235::aid-ejoc3235>3.0.co;2-7

Reference yield: 80.0%

: 308266-11-7
1-(benzyloxymethyl)-1-(dibenzylamino)cyclopropane

: 115652-52-3
1-amino-1-(hydroxymethyl)cyclopropane hydrochloride

: 1-benzyloxymethyl-cyclopropylamine; hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; for 72h; under 750.06 Torr;
DOI:10.1002/1099-0690(200009)2000:18<3235::aid-ejoc3235>3.0.co;2-7

Reference yield:

: 308266-11-7
1-(benzyloxymethyl)-1-(dibenzylamino)cyclopropane

: 308266-24-2
(N-tert-butoxycarbonyl)-1-(benzyloxymethyl)cyclopropylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / H₂; aq. HCl / 5 percent Pd/C / methanol / 72 h / 750.06 Torr

2: 82 percent / Et₃N; DMAP / methanol / 24 h / 20 °C

With hydrogenchloride; dmap; hydrogen; triethylamine; palladium on activated charcoal; In methanol; 1: Hydrogenolysis / 2: Acylation;
DOI:10.1002/1099-0690(200009)2000:18<3235::aid-ejoc3235>3.0.co;2-7